منابع مشابه
Tasteless Food Reward
Food palatability acts on the dopaminergic reward system to override homeostatic control; however, whether postingestive calorie load in the absence of taste affects this system remains unclear. In this issue of Neuron, de Araujo et al. show that mice lacking functional "sweet" taste receptors (trpm5-/-) develop a preference for sucrose by activating the mesolimbic dopamine-accumbal pathway, so...
متن کاملIntravascular Food Reward
Consumption of calorie-containing sugars elicits appetitive behavioral responses and dopamine release in the ventral striatum, even in the absence of sweet-taste transduction machinery. However, it is unclear if such reward-related postingestive effects reflect preabsorptive or postabsorptive events. In support of the importance of postabsorptive glucose detection, we found that, in rat behavio...
متن کاملThe parsing of food reward.
WHAT IS IT THAT IS habit-forming about food? Sweet foods and fatty foods are habit-forming and sweet-fatty foods perhaps more than doubly so. Many kitchen and industrial experiments have gone into the determination of the amounts of sugar and butter to optimize the palatability of a given meal or substance. But humans also seek out bitter and tart substances. Cattle seek out and ingest alfalfa,...
متن کاملFood reward, hyperphagia, and obesity.
Given the unabated obesity problem, there is increasing appreciation of expressions like "my eyes are bigger than my stomach," and recent studies in rodents and humans suggest that dysregulated brain reward pathways may be contributing not only to drug addiction but also to increased intake of palatable foods and ultimately obesity. After describing recent progress in revealing the neural pathw...
متن کاملA model of food reward learning with dynamic reward exposure
The process of conditioning via reward learning is highly relevant to the study of food choice and obesity. Learning is itself shaped by environmental exposure, with the potential for such exposures to vary substantially across individuals and across place and time. In this paper, we use computational techniques to extend a well-validated standard model of reward learning, introducing both subs...
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ژورنال
عنوان ژورنال: Neuron
سال: 2008
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2008.03.004